Ovarian and breast cancer are two of the most common cancers affecting women. While they occur in different parts of the body, there is a strong biological link between them—especially through genetics.

A key connection is mutations in the BRCA1 and BRCA2 genes. According to the American Cancer Society, women with breast cancer have twice the risk of developing ovarian cancer compared to the general population.

Research shows that women with a BRCA1 mutation have up to a 72% lifetime risk of breast cancer and up to a 44% risk of ovarian cancer. For those with a BRCA2 mutation, the risks are up to 69% for breast cancer and 17% for ovarian cancer.

These gene mutations can be inherited from either parent, making family history of either cancer a significant risk factor—even if no family member has had both types.

Women from families with multiple cases of breast or ovarian cancer may benefit from genetic testing. Understanding your genetic makeup can guide preventive strategies and early detection plans with your healthcare provider.

Other shared risk factors include age, obesity, not having children, and long-term hormone replacement therapy after menopause.

To reduce cancer risk, some high-risk individuals consider preventive surgeries, such as a mastectomy or oophorectomy, which involve the removal of breasts, ovaries, and fallopian tubes.

Early awareness, genetic insight, and medical guidance can be powerful tools in managing cancer risk and protecting long-term health.